Ontology highlight
ABSTRACT:
SUBMITTER: Cheedipudi S
PROVIDER: S-EPMC3912789 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Cheedipudi Sirisha S Genolet Oriana O Dobreva Gergana G
Frontiers in genetics 20140204
During embryonic development a large number of widely differing and specialized cell types with identical genomes are generated from a single totipotent zygote. Tissue specific transcription factors cooperate with epigenetic modifiers to establish cellular identity in differentiated cells and epigenetic regulatory mechanisms contribute to the maintenance of distinct chromatin states and cell-type specific gene expression patterns, a phenomenon referred to as epigenetic memory. This is accomplish ...[more]