Ontology highlight
ABSTRACT:
SUBMITTER: Perfeito L
PROVIDER: S-EPMC3912910 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Perfeito L L Sousa A A Sousa A A Bataillon T T Gordo I I
Evolution; international journal of organic evolution 20130902 1
Unraveling the factors that determine the rate of adaptation is a major question in evolutionary biology. One key parameter is the effect of a new mutation on fitness, which invariably depends on the environment and genetic background. The fate of a mutation also depends on population size, which determines the amount of drift it will experience. Here, we manipulate both population size and genotype composition and follow adaptation of 23 distinct Escherichia coli genotypes. These have previousl ...[more]