Ontology highlight
ABSTRACT:
SUBMITTER: Maffei S
PROVIDER: S-EPMC3913460 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Maffei Silvia S De Felice Claudio C Cannarile Pierpaolo P Leoncini Silvia S Signorini Cinzia C Pecorelli Alessandra A Montomoli Barbara B Lunghetti Stefano S Ciccoli Lucia L Durand Thierry T Favilli Roberto R Hayek Joussef J
Mediators of inflammation 20140112
Rett syndrome (RTT) is a devastating neurodevelopmental disorder with a 300-fold increased risk rate for sudden cardiac death. A subclinical myocardial biventricular dysfunction has been recently reported in RTT by our group and found to be associated with an enhanced oxidative stress (OS) status. Here, we tested the effects of the naturally occurring antioxidants ω-3 polyunsaturated fatty acids (ω-3 PUFAs) on echocardiographic parameters and systemic OS markers in a population of RTT patients w ...[more]