Ontology highlight
ABSTRACT:
SUBMITTER: Henderson SJ
PROVIDER: S-EPMC3914468 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Henderson Simon J SJ Andersson Christin C Narwal Rajesh R Janson Juliette J Goldschmidt Tom J TJ Appelkvist Paulina P Bogstedt Anna A Steffen Ann-Charlott AC Haupts Ulrich U Tebbe Jan J Freskgård Per Ola PO Jermutus Lutz L Burrell Matthew M Fowler Susan B SB Webster Carl I CI
Brain : a journal of neurology 20131120 Pt 2
Alzheimer's disease is characterized by the accumulation of amyloid deposits in the brain and the progressive loss of cognitive functions. Although the precise role of amyloid-β in disease progression remains somewhat controversial, many efforts to halt or reverse disease progression have focussed on reducing its synthesis or enhancing its removal. It is believed that brain and peripheral soluble amyloid-β are in equilibrium and it has previously been hypothesized that a reduction in peripheral ...[more]