Ontology highlight
ABSTRACT:
SUBMITTER: Li L
PROVIDER: S-EPMC3915774 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Li Lei L Liu Yonghui Y Wan Yue Y Li Yanhong Y Chen Xi X Zhao Wei W Wang Peng George PG
Organic letters 20131011 21
An N-acetylhexosamine 1-kinase from Bifidobacterium infantis (NahK_15697), a guanosine 5'-diphosphate (GDP)-mannose pyrophosphorylase from Pyrococcus furiosus (PFManC), and an Escherichia coli inorganic pyrophosphatase (EcPpA) were used efficiently for a one-pot three-enzyme synthesis of GDP-mannose, GDP-glucose, their derivatives, and GDP-talose. This study represents the first facile and efficient enzymatic synthesis of GDP-sugars and derivatives starting from monosaccharides and derivatives. ...[more]