Ontology highlight
ABSTRACT:
SUBMITTER: Wu T
PROVIDER: S-EPMC3916361 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wu Tao T Schwender Holger H Ruczinski Ingo I Murray Jeffrey C JC Marazita Mary L ML Munger Ronald G RG Hetmanski Jacqueline B JB Parker Margaret M MM Wang Ping P Murray Tanda T Taub Margaret M Li Shuai S Redett Richard J RJ Fallin M Daniele MD Liang Kung Yee KY Wu-Chou Yah Huei YH Chong Samuel S SS Yeow Vincent V Ye Xiaoqian X Wang Hong H Huang Shangzhi S Jabs Ethylin W EW Shi Bing B Wilcox Allen J AJ Jee Sun Ha SH Scott Alan F AF Beaty Terri H TH
PloS one 20140206 2
Nonsyndromic cleft palate (CP) is one of the most common human birth defects and both genetic and environmental risk factors contribute to its etiology. We conducted a genome-wide association study (GWAS) using 550 CP case-parent trios ascertained in an international consortium. Stratified analysis among trios with different ancestries was performed to test for GxE interactions with common maternal exposures using conditional logistic regression models. While no single nucleotide polymorphism (S ...[more]