Immune aspects of the breast tumor microenvironment.
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ABSTRACT:
SUBMITTER: Chawla A
PROVIDER: S-EPMC3917569 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Publications
Immune aspects of the breast tumor microenvironment.
Chawla Akhil A Alatrash Gheath G Wu Yun Y Mittendorf Elizabeth A EA
Breast cancer management 20130501 3
The immune response in the tumor microenvironment is complex, consisting of cells from both the adaptive and innate immune systems. The phenotype and function of these cells are dictated by cytokines present in the microenvironment, as well as by the interactions of these cells with the tumor cells and each other. Technological advances have allowed investigators to better identify the specific immune cells present and immune-related gene signatures overexpressed in the tumor microenvironment. I ...[more]
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