Ontology highlight
ABSTRACT:
SUBMITTER: Bauters D
PROVIDER: S-EPMC3917933 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Bauters Dries D Van Hul Matthias M Lijnen Henri Roger HR
Adipocyte 20131105 1
Growth of adipose tissue involves differentiation of preadipocytes into mature lipid-containing adipocytes. The matrix metalloproteinases (MMPs) are known regulators of adipose tissue biology, and previous studies suggested a key role for gelatinase B (MMP-9) in adipogenesis. In the present study we have evaluated a potential functional role of MMP-9 by performing gene silencing in 3T3-F442A preadipocytes. At the end of a 12-day differentiation period, no significant differences were observed be ...[more]