Ontology highlight
ABSTRACT:
SUBMITTER: Bandeiras C
PROVIDER: S-EPMC3919732 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Bandeiras Cátia C Trovoada Maria Jesus MJ Gonçalves Lígia A LA Marinho Cláudio R F CR Turner Louise L Hviid Lars L Penha-Gonçalves Carlos C Gomes M Gabriela M MG
PloS one 20140210 2
After remarkable success of vector control campaigns worldwide, concerns about loss of immunity against Plasmodium falciparum due to lack of exposure to the parasite are relevant since an increase of severe cases in less immune individuals is expected. We present a mathematical model to investigate the impact of reducing exposure to the parasite on the immune repertoire against P. falciparum erythrocyte membrane protein 1 (PfEMP1) variants. The model was parameterized with data from Príncipe Isl ...[more]