Circulating microRNAs as potential biomarkers of aerobic exercise capacity.

ABSTRACT: Purpose microRNAs (miRs) are crucial intracellular mediators of various biological processes, also affecting the cardiovascular system. Recently, it has been shown that miRs circulate extracellularly in the bloodstream and that such circulating miRs change in response to physical activity. Therefore, the purpose of the current study was to investigate heart/muscle specific and inflammation related miRs in plasma of individuals before, directly after, and 24 h after a marathon run and to analyze their relation to conventional biochemical, cardiovascular, and performance indexes. Male endurance athletes (n =14) were recruited for the study after performing a battery of cardiac functional tests. Blood samples were collected before, directly after, and 24 h after a public marathon run. miR-1,

SUBMITTER: Mooren FC 

PROVIDER: S-EPMC3920240 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature