Ontology highlight
ABSTRACT:
SUBMITTER: Pullen N
PROVIDER: S-EPMC3921180 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Pullen Nick N Morris Richard J RJ
PloS one 20140211 2
Inferring parameters for models of biological processes is a current challenge in systems biology, as is the related problem of comparing competing models that explain the data. In this work we apply Skilling's nested sampling to address both of these problems. Nested sampling is a Bayesian method for exploring parameter space that transforms a multi-dimensional integral to a 1D integration over likelihood space. This approach focuses on the computation of the marginal likelihood or evidence. Th ...[more]