Ontology highlight
ABSTRACT:
SUBMITTER: Cho SY
PROVIDER: S-EPMC3924006 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Cho Sung Yoon SY Huh Rimm R Chang Mi Sun MS Lee Jieun J Kwun Younghee Y Maeng Se Hyun SH Kim Su Jin SJ Sohn Young Bae YB Park Sung Won SW Kwon Eun-Kyung EK Han Sun Ju SJ Jung Jooyoun J Jin Dong-Kyu DK
Journal of Korean medical science 20140128 2
Hunter syndrome (or mucopolysaccharidosis type II [MPS II]) arises because of a deficiency in the lysosomal enzyme iduronate-2-sulfatase. Short stature is a prominent and consistent feature in MPS II. Enzyme replacement therapy (ERT) with idursulfase (Elaprase®) or idursulfase beta (Hunterase®) have been developed for these patients. The effect of ERT on the growth of Korean patients with Hunter syndrome was evaluated at a single center. This study comprised 32 patients, who had received ERT for ...[more]