Ontology highlight
ABSTRACT:
SUBMITTER: Twal WO
PROVIDER: S-EPMC3925209 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Twal Waleed O WO Klatt Sandra C SC Harikrishnan Keerthi K Gerges Ebtesam E Cooley Marion A MA Trusk Thomas C TC Zhou Boran B Gabr Mohamed G MG Shazly Tarek T Lessner Susan M SM Markwald Roger R RR Argraves W Scott WS
Annals of biomedical engineering 20130814 7
To meet demands of vascular reconstruction, there is a need for prosthetic alternatives to natural blood vessels. Here we explored a new conduit fabrication approach. Macroporous, gelatin microcarriers laden with human umbilical vein endothelial cells and aortic smooth muscle cells were dispensed into tubular agarose molds and found to adhere to form living tubular tissues. The ability of cellularized microcarriers to adhere to one another involved cellular and extracellular matrix bridging that ...[more]