Ontology highlight
ABSTRACT:
SUBMITTER: Bridges AA
PROVIDER: S-EPMC3926015 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Bridges Andrew A AA Zhang Huaiying H Mehta Shalin B SB Occhipinti Patricia P Tani Tomomi T Gladfelter Amy S AS
Proceedings of the National Academy of Sciences of the United States of America 20140127 6
Septins assemble into filaments and higher-order structures that act as scaffolds for diverse cell functions including cytokinesis, cell polarity, and membrane remodeling. Despite their conserved role in cell organization, little is known about how septin filaments elongate and are knitted together into higher-order assemblies. Using fluorescence correlation spectroscopy, we determined that cytosolic septins are in small complexes, suggesting that septin filaments are not formed in the cytosol. ...[more]