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Individual differences in autistic traits predict the perception of direct gaze for males, but not for females.

ABSTRACT: Despite the emphasis of autism spectrum disorders as a continuum of atypical social behaviors and the sexual heterogeneity of phenotypic manifestations, whether gaze processing constitutes an autistic endophenotype in both sexes remains unclear. Using the Autism-Spectrum Quotient and a psychophysical approach in a normal population (N?=?128), here we demonstrated that individual differences in autistic traits predicted direct-gaze perception for males, but not for females. Our findings suggest that direct-gaze perception may not constitute an autistic endophenotype in both sexes, and highlight the importance of sex differences when considering relationships between autistic traits and behaviors.

SUBMITTER: Matsuyoshi D

PROVIDER: S-EPMC3926258 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature

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Individual differences in autistic traits predict the perception of direct gaze for males, but not for females.

Matsuyoshi Daisuke D Kuraguchi Kana K Tanaka Yumiko Y Uchida Seina S Ashida Hiroshi H Watanabe Katsumi K

Molecular autism 20140212 1

Despite the emphasis of autism spectrum disorders as a continuum of atypical social behaviors and the sexual heterogeneity of phenotypic manifestations, whether gaze processing constitutes an autistic endophenotype in both sexes remains unclear. Using the Autism-Spectrum Quotient and a psychophysical approach in a normal population (N = 128), here we demonstrated that individual differences in autistic traits predicted direct-gaze perception for males, but not for females. Our findings suggest t ...[more]

PMID: 24521089

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