Ontology highlight
ABSTRACT:
SUBMITTER: Enna SJ
PROVIDER: S-EPMC3927317 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Enna S J SJ McCarson Kenneth E KE
Current protocols in pharmacology 20131202
Described in this unit are ligand-binding assays for GABAA , GABAB , and the homomeric ρ GABAA (formerly GABAC ) receptor recognition sites in brain tissue. Although GABA binding sites are present in peripheral organs, most research is directed toward examining these receptors in the CNS. These assays may also be used to determine the affinity of an unlabeled compound for the GABA binding sites. Excluded from the unit are ligand-binding assays for other components of the GABAA receptor complex, ...[more]