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Forqs: forward-in-time simulation of recombination, quantitative traits and selection.

ABSTRACT: forqs is a forward-in-time simulation of recombination, quantitative traits and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations due to recombination and/or selection on polygenic quantitative traits.forqs is implemented as a command-line C++ program. Source code and binary executables for Linux, OSX and Windows are freely available under a permissive BSD license: https://bitbucket.org/dkessner/forqs.

SUBMITTER: Kessner D

PROVIDER: S-EPMC3928523 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature

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forqs: forward-in-time simulation of recombination, quantitative traits and selection.

Kessner Darren D Novembre John J

Bioinformatics (Oxford, England) 20131210 4

<h4>Summary</h4>forqs is a forward-in-time simulation of recombination, quantitative traits and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations due to recombination and/or selection on polygenic quantitative traits.<h4>Availability and implementation</h4>forqs is implemented as a command-line C++ program. Source code and binary executables for Linux, OSX and Windows are fr ...[more]

PMID: 24336146

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