Ontology highlight
ABSTRACT:
SUBMITTER: Cheng TY
PROVIDER: S-EPMC3930969 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Cheng Tsu-Yao TY Wu Ming-Shiang MS Hua Kuo-Tai KT Kuo Min-Liang ML Lin Ming-Tsan MT
World journal of gastroenterology 20140201 7
Gastric cancer (GC) is the second leading cause of cancer-related death. The poor survival rate may reflect the relatively aggressive tumor biology of GC. Recently, the importance of the tumor microenvironment in carcinogenesis has emerged. In the tumor microenvironment, tumor cells and the surrounding stromal cells aberrantly secrete matricellular proteins capable of modulating carcinogenesis and regulating metastasis. The Cyr61/CTGF/Nov (CCN) proteins are a family of matricellular proteins wit ...[more]