Contrast enhanced CT attenuation correlates with the GAG content of bovine meniscus.
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ABSTRACT:
SUBMITTER: Lakin BA
PROVIDER: S-EPMC3931129 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Publications
Contrast enhanced CT attenuation correlates with the GAG content of bovine meniscus.
Lakin Bejamin A BA Grasso Daniel J DJ Stewart Rachel C RC Freedman Jonathan D JD Snyder Brian D BD Grinstaff Mark W MW
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20130705 11
We determined whether contrast-enhanced computed tomography (CECT) attenuation obtained using a µCT scanner correlated with the glycosaminoglycan (GAG) content and distribution in ex vivo bovine menisci. Bovine samples were immersed in different concentrations of the contrast agents CA4+ and Ioxaglate, and the µCT images were compared to Safranin-O staining. CA4+ and Ioxaglate diffusion-in kinetics and the correlation between their CECT attenuations and GAG content were investigated. CA4+ and Io ...[more]
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