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Rare presentation of botulism with generalized fasciculations.

ABSTRACT: Botulism is a dreadful, life-threatening, neuroparalytic disease caused by gram positive bacteria Clostridium botulinum. Food borne botulism has been described following ingestion of preformed toxins in canned food or food products that have not been preserved properly. Botulinum toxin acts on neuromuscular junction and manifests as ophthalmoplegia, bulbar and limb weakness, and autonomic features along with respiratory compromise. The literature and case reports regarding neuroparalytic botulism in India are sparse. Generalized fasciculations have been rarely reported in literature as manifestation of food borne botulism. We present a 35-year-male presenting with usual features described, but with prominent generalized fasciculations which are rare, and which rapidly responded to treatment.

SUBMITTER: Arora A

PROVIDER: S-EPMC3931218 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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Rare presentation of botulism with generalized fasciculations.

Arora Amit A Sharma Chandra Mohan CM Kumawat Bl B Khandelwal Dinesh D

International journal of applied & basic medical research 20140101 1

Botulism is a dreadful, life-threatening, neuroparalytic disease caused by gram positive bacteria Clostridium botulinum. Food borne botulism has been described following ingestion of preformed toxins in canned food or food products that have not been preserved properly. Botulinum toxin acts on neuromuscular junction and manifests as ophthalmoplegia, bulbar and limb weakness, and autonomic features along with respiratory compromise. The literature and case reports regarding neuroparalytic botulis ...[more]

PMID: 24600582

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