Bacterial cytokinesis: From Z ring to divisome.
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ABSTRACT:
SUBMITTER: Lutkenhaus J
PROVIDER: S-EPMC3931253 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Publications
Bacterial cytokinesis: From Z ring to divisome.
Lutkenhaus Joe J Pichoff Sebastien S Du Shishen S
Cytoskeleton (Hoboken, N.J.) 20120830 10
Ancestral homologues of the major eukaryotic cytoskeletal families, tubulin and actin, play critical roles in cytokinesis of bacterial cells. FtsZ is the ancestral homologue of tubulin and assembles into the Z ring that determines the division plane. FtsA, a member of the actin family, is involved in coordinating cell wall synthesis during cytokinesis. FtsA assists in the formation of the Z ring and also has a critical role in recruiting downstream division proteins to the Z ring to generate the ...[more]
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