Ontology highlight
ABSTRACT:
SUBMITTER: Gertz EM
PROVIDER: S-EPMC3932042 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Gertz Edward Michael EM Hiekkalinna Tero T Digabel Sébastien Le SL Audet Charles C Terwilliger Joseph D JD Schäffer Alejandro A AA
BMC bioinformatics 20140217
<h4>Background</h4>PSEUDOMARKER is a software package that performs joint linkage and linkage disequilibrium analysis between a marker and a putative disease locus. A key feature of PSEUDOMARKER is that it can combine case-controls and pedigrees of varying structure into a single unified analysis. Thus it maximizes the full likelihood of the data over marker allele frequencies or conditional allele frequencies on disease and recombination fraction.<h4>Results</h4>The new version 2.0 uses the sof ...[more]