Ontology highlight
ABSTRACT:
SUBMITTER: Dane EL
PROVIDER: S-EPMC3932237 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Dane Eric L EL Chin Stacy L SL Grinstaff Mark W MW
ACS macro letters 20131001 10
The first synthesis of poly-amido-saccharides (PASs) from a galactose(gal)-derived β-lactam sugar monomer is reported. The polymers are prepared using a controlled anionic ring-opening polymerization and characterized by NMR, optical rotation, IR, and GPC. Galactose-derived PASs display high solubility in aqueous solutions and are noncytotoxic to HepG2, CHO, and HeLa cell lines. To evaluate whether gal-derived PASs are recognized by the gal-specific lectin present on human hepatocytes, cellular ...[more]