Ontology highlight
ABSTRACT:
SUBMITTER: Laforteza BN
PROVIDER: S-EPMC3934209 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Laforteza Brian N BN Pickworth Mark M Macmillan David W C DW
Angewandte Chemie (International ed. in English) 20130902 43
Dressed to the nines: The first enantioselective total synthesis of (-)-minovincine has been accomplished in nine chemical steps and 13 % overall yield. A novel, one-step Diels-Alder/β-elimination/conjugate addition organocascade sequence allowed rapid access to the central tetracyclic core in an asymmetric manner. Boc=tert-butoxycarbonyl, LG=leaving group, PMB=para-methoxybenzyl. ...[more]