Ontology highlight
ABSTRACT:
SUBMITTER: Dai W
PROVIDER: S-EPMC3935967 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Dai Wentao W Song Tingrui T Wang Xuan X Jin Xiaoyang X Deng Lizong L Wu Aiping A Jiang Taijiao T
PloS one 20140226 2
Many template-based modeling (TBM) methods have been developed over the recent years that allow for protein structure prediction and for the study of structure-function relationships for proteins. One major problem all TBM algorithms face, however, is their unsatisfactory performance when proteins under consideration are low-homology. To improve the performance of TBM methods for such targets, a novel model evaluation method was developed here, and named MEFTop. Our novel method focuses on evalu ...[more]