Ontology highlight
ABSTRACT:
SUBMITTER: Diwan D
PROVIDER: S-EPMC3937000 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Diwan Deepti D Komazaki Shun S Suzuki Miho M Nemoto Naoto N Aita Takuyo T Satake Akiko A Nishigaki Koichi K
BMC genomics 20140219
<h4>Background</h4>Even in the age of next-generation sequencing (NGS), it has been unclear whether or not cells within a single organism have systematically distinctive genomes. Resolving this question, one of the most basic biological problems associated with DNA mutation rates, can assist efforts to elucidate essential mechanisms of cancer.<h4>Results</h4>Using genome profiling (GP), we detected considerable systematic variation in genome sequences among cells in individual woody plants. The ...[more]