Ontology highlight
ABSTRACT:
SUBMITTER: Xia W
PROVIDER: S-EPMC3938763 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Xia Wei W Jiang Ying Y Li Yuanyuan Y Wan Yanjian Y Liu Juan J Ma Yue Y Mao Zhenxing Z Chang Huailong H Li Gengqi G Xu Bing B Chen Xi X Xu Shunqing S
PloS one 20140228 2
Exposure to bisphenol A (BPA), a monomer widely used to manufacture polycarbonate plastics, has been reported to be associated with abnormalities of liver function and hepatic damage. However, the molecular mechanism under the pathogenesis of hepatic injury is unclear. In this study, the effect of perinatal exposure to BPA at the reference dose of 50 µg/kg/day on the apoptotic index in the liver of rat offspring was investigated. Increased levels of ALT and enhanced cell apoptosis were observed ...[more]