Ontology highlight
ABSTRACT:
SUBMITTER: Wang W
PROVIDER: S-EPMC3939005 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wang Wei W Ingles Sue Ann SA Torres-Mejía Gabriela G Stern Mariana C MC Stanczyk Frank Z FZ Schwartz Gary G GG Nelson David O DO Fejerman Laura L Wolff Roger K RK Slattery Martha L ML John Esther M EM
International journal of molecular epidemiology and genetics 20140217 1
Genome-wide association studies (GWAS) have identified common polymorphisms in or near GC, CYP2R1, CYP24A1, and NADSYN1/DHCR7 genes to be associated with circulating levels of 25-hydroxyvitamin D [25(OH)D] in European populations. To replicate these GWAS findings, we examined six selected polymorphisms from these regions and their relation with circulating 25(OH)D levels in 1,605 Hispanic women (629 U.S. Hispanics and 976 Mexicans) and 354 non-Hispanic White (NHW) women. We also assessed the pot ...[more]