Ontology highlight
ABSTRACT:
SUBMITTER: Schleiss MR
PROVIDER: S-EPMC3939465 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Schleiss Mark R MR McAllister Shane S Armién Anibal G AG Hernandez-Alvarado Nelmary N Fernández-Alarcón Claudia C Zabeli Jason C JC Ramaraj Thiruvarangan T Crow John A JA McVoy Michael A MA
Viruses 20140127 2
Development of a vaccine against congenital infection with human cytomegalovirus is complicated by the issue of re-infection, with subsequent vertical transmission, in women with pre-conception immunity to the virus. The study of experimental therapeutic prevention of re-infection would ideally be undertaken in a small animal model, such as the guinea pig cytomegalovirus (GPCMV) model, prior to human clinical trials. However, the ability to model re-infection in the GPCMV model has been limited ...[more]