Amish revisited: next-generation sequencing studies of psychiatric disorders among the Plain people.
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ABSTRACT:
SUBMITTER: Hou L
PROVIDER: S-EPMC3941079 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Publications
Amish revisited: next-generation sequencing studies of psychiatric disorders among the Plain people.
Hou Liping L Faraci Gloria G Chen David T W DT Kassem Layla L Schulze Thomas G TG Shugart Yin Yao YY McMahon Francis J FJ
Trends in genetics : TIG 20130217 7
The rapid development of next-generation sequencing (NGS) technology has led to renewed interest in the potential contribution of rarer forms of genetic variation to complex non-mendelian phenotypes such as psychiatric illnesses. Although challenging, family-based studies offer some advantages, especially in communities with large families and a limited number of founders. Here we revisit family-based studies of mental illnesses in traditional Amish and Mennonite communities--known collectively ...[more]
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