Ontology highlight
ABSTRACT:
SUBMITTER: Murphy BP
PROVIDER: S-EPMC3941155 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Murphy Brendan P BP Pang Terence Y TY Hannan Anthony J AJ Proffitt Tina-Marie TM McConchie Mirabel M Kerr Melissa M Markulev Connie C O'Donnell Colin C McGorry Patrick D PD Berger Gregor E GE
Schizophrenia research and treatment 20140205
Objective. It has been suggested that atypical antipsychotics confer their effects via brain-derived neurotrophic factor (BDNF). We investigated the effect of quetiapine on serum levels of BDNF and vascular endothelial growth factor (VEGF) in drug-naive first-episode psychosis subjects. Methods. Fifteen patients drawn from a larger study received quetiapine treatment for twelve weeks. Baseline levels of serum BDNF and VEGF were compared to age- and sex-matched healthy controls and to levels foll ...[more]