Ontology highlight
ABSTRACT:
SUBMITTER: Andrianasolo EH
PROVIDER: S-EPMC3944532 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Marine drugs 20140220 2
Chemical and biological investigation of the cultured marine soft coral Xenia elongata led to the isolation of two new diterpenes (2, 3). Their structures were elucidated using a combination of NMR and mass spectrometry. Biological evaluations and assessments were determined using the specific apoptosis induction assay based on genetically engineered mammalian cell line D3 deficient in Bak and Bax and derived from a mouse epithelial cell. The diterpenes induce apoptosis in low micromolar concent ...[more]