Alterations in lung gene expression in streptozotocin-induced diabetic rats.
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ABSTRACT:
SUBMITTER: van Lunteren E
PROVIDER: S-EPMC3945062 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Alterations in lung gene expression in streptozotocin-induced diabetic rats.
van Lunteren Erik E Moyer Michelle M Spiegler Sarah S
BMC endocrine disorders 20140115
<h4>Background</h4>Diabetes profoundly affects gene expression in organs such as heart, skeletal muscle, kidney and liver, with areas of perturbation including carbohydrate and lipid metabolism, oxidative stress, and protein ubiquitination. Type 1 diabetes impairs lung function, but whether gene expression alterations in the lung parallel those of other tissue types is largely unexplored.<h4>Methods</h4>Lung from a rat model of diabetes mellitus induced by streptozotocin was subjected to gene ex ...[more]
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