Refractive error and risk of early or late age-related macular degeneration: a systematic review and meta-analysis.

ABSTRACT:

Objective

To summarize relevant evidence investigating the associations between refractive error and age-related macular degeneration (AMD).

Design

Systematic review and meta-analysis.

Methods

We searched Medline, Web of Science, and Cochrane databases as well as the reference lists of retrieved articles to identify studies that met the inclusion criteria. Extracted data were combined using a random-effects meta-analysis. Studies that were pertinent to our topic but did not meet the criteria for quantitative analysis were reported in a systematic review instead.

Main outcome measures

Pooled odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between refractive error (hyperopia, myopia, per-diopter increase in spherical equivalent [SE] towa

SUBMITTER: Li Y 

PROVIDER: S-EPMC3946285 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature