Ontology highlight
ABSTRACT:
SUBMITTER: Ahmed Hassan LE
PROVIDER: S-EPMC3946547 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Ahmed Hassan Loiy Elsir LE Khadeer Ahamed Mohamed B MB Abdul Majid Aman Shah AS Iqbal Muhammad Adnan MA Al Suede Fouad Saleih R FS Haque Rosenani A RA Ismail Zhari Z Ein Oon Chern OC Majid Amin Malik Shah Abdul AM
PloS one 20140307 6
Tephrosia apollinea is a perennial shrublet widely distributed in Africa and is known to have medicinal properties. The current study describes the bio-assay (cytotoxicity) guided isolation of (-)-pseudosemiglabrin from the aerial parts of T. apollinea. The structural and stereochemical features have been described using spectral and x-ray crystallographic techniques. The cytotoxicity of isolated compound was evaluated against nine cancer cell lines. In addition, human fibroblast was used as a m ...[more]