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Group A streptococcal emm type prevalence among symptomatic children in Cape Town and potential vaccine coverage.


ABSTRACT: The molecular epidemiology of group A streptococcal pharyngeal infections in children in the Vanguard Community of Cape Town revealed 26 emm types among 157 isolates from 742 subjects. Coverage of a 30-valent vaccine is predicted to be 95% of pharyngitis cases in this population at high risk of rheumatic fever.

SUBMITTER: Engel ME 

PROVIDER: S-EPMC3947201 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature

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Group A streptococcal emm type prevalence among symptomatic children in Cape Town and potential vaccine coverage.

Engel Mark E ME   Muhamed Babu B   Whitelaw Andrew C AC   Musvosvi Munyaradzi M   Mayosi Bongani M BM   Dale James B JB  

The Pediatric infectious disease journal 20140201 2


The molecular epidemiology of group A streptococcal pharyngeal infections in children in the Vanguard Community of Cape Town revealed 26 emm types among 157 isolates from 742 subjects. Coverage of a 30-valent vaccine is predicted to be 95% of pharyngitis cases in this population at high risk of rheumatic fever. ...[more]

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