Ontology highlight
ABSTRACT:
SUBMITTER: Ryan BM
PROVIDER: S-EPMC3947351 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Ryan Bríd M BM Zanetti Krista A KA Robles Ana I AI Schetter Aaron J AJ Goodman Julie J Hayes Richard B RB Huang Wen-Yi WY Gunter Mark J MJ Yeager Meredith M Burdette Laurie L Berndt Sonja I SI Harris Curtis C CC
International journal of cancer 20131114 6
Chronic inflammation has been implicated in the etiology of colorectal adenoma and cancer; however, few key inflammatory genes mediating this relationship have been identified. In this study, we investigated the association of germline variation in innate immunity genes in relation to the risk of colorectal neoplasia. Our study was based on the analysis of samples collected from the prostate, lung, colorectal and ovarian (PLCO) Cancer Screening Trial. We investigated the association between 196 ...[more]