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Stabilized porous liposomes with encapsulated Gd-labeled dextran as a highly efficient MRI contrast agent.

ABSTRACT: A highly efficient contrast agent for magnetic resonance imaging was developed by encapsulating gadolinium within a stabilized porous liposome. The highly porous membrane leads to a high relaxivity of the encapsulated Gd. The stability of the liposome was improved by forming a polymer network within the bilayer membrane.

SUBMITTER: Cheng Z 

PROVIDER: S-EPMC3947407 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature

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Stabilized porous liposomes with encapsulated Gd-labeled dextran as a highly efficient MRI contrast agent.

Cheng Zhiliang Z   Al Zaki Ajlan A   Jones Ian W IW   Hall Henry K HK   Aspinwall Craig A CA   Tsourkas Andrew A  

Chemical communications (Cambridge, England) 20140124 19

A highly efficient contrast agent for magnetic resonance imaging was developed by encapsulating gadolinium within a stabilized porous liposome. The highly porous membrane leads to a high relaxivity of the encapsulated Gd. The stability of the liposome was improved by forming a polymer network within the bilayer membrane. ...[more]

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