Control strategies to prevent total hip replacement-related infections: a systematic review and mixed treatment comparison.

ABSTRACT:

Objective

To synthesise the available evidence and estimate the comparative efficacy of control strategies to prevent total hip replacement (THR)-related surgical site infections (SSIs) using a mixed treatment comparison.

Design

Systematic review and mixed treatment comparison.

Setting

Hospital and other healthcare settings.

Participants

Patients undergoing THR.

Primary and secondary outcome measures

The number of THR-related SSIs occurring following the surgical operation.

Results

12 studies involving 123 788 THRs and 9 infection control strategies were identified. The strategy of 'systemic antibiotics+antibiotic-impregnated cement+conventional ventilation' significantly reduced the risk of THR-related SSI compared with the referent strategy (no

SUBMITTER: Zheng H 

PROVIDER: S-EPMC3948634 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature