Ontology highlight
ABSTRACT:
SUBMITTER: Lopez-Lopez E
PROVIDER: S-EPMC3948785 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
López-López Elixabet E Gutiérrez-Camino Ángela Á Piñán Maria Ángeles MÁ Sánchez-Toledo José J Uriz Jose Javier JJ Ballesteros Javier J García-Miguel Purificación P Navajas Aurora A García-Orad África Á
PloS one 20140310 3
Despite the clinical success of acute lymphoblastic leukemia (ALL) therapy, toxicity is frequent. Therefore, it would be useful to identify predictors of adverse effects. In the last years, several studies have investigated the relationship between genetic variation and treatment-related toxicity. However, most of these studies are focused in coding regions. Nowadays, it is known that regions that do not codify proteins, such as microRNAs (miRNAs), may have an important regulatory function. MiRN ...[more]