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Enabling transparent and collaborative computational analysis of 12 tumor types within The Cancer Genome Atlas.


ABSTRACT: The Cancer Genome Atlas Pan-Cancer Analysis Working Group collaborated on the Synapse software platform to share and evolve data, results and methodologies while performing integrative analysis of molecular profiling data from 12 tumor types. The group's work serves as a pilot case study that provides (i) a template for future large collaborative studies; (ii) a system to support collaborative projects; and (iii) a public resource of highly curated data, results and automated systems for the evaluation of community-developed models.

SUBMITTER: Omberg L 

PROVIDER: S-EPMC3950337 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature

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Enabling transparent and collaborative computational analysis of 12 tumor types within The Cancer Genome Atlas.

Omberg Larsson L   Ellrott Kyle K   Yuan Yuan Y   Kandoth Cyriac C   Wong Chris C   Kellen Michael R MR   Friend Stephen H SH   Stuart Josh J   Liang Han H   Margolin Adam A AA  

Nature genetics 20131001 10


The Cancer Genome Atlas Pan-Cancer Analysis Working Group collaborated on the Synapse software platform to share and evolve data, results and methodologies while performing integrative analysis of molecular profiling data from 12 tumor types. The group's work serves as a pilot case study that provides (i) a template for future large collaborative studies; (ii) a system to support collaborative projects; and (iii) a public resource of highly curated data, results and automated systems for the eva  ...[more]

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