Ontology highlight
ABSTRACT:
SUBMITTER: Macinnis RJ
PROVIDER: S-EPMC3950816 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Macinnis Robert J RJ Antoniou Antonis C AC Eeles Rosalind A RA Severi Gianluca G Al Olama Ali Amin AA McGuffog Lesley L Kote-Jarai Zsofia Z Guy Michelle M O'Brien Lynne T LT Hall Amanda L AL Wilkinson Rosemary A RA Sawyer Emma E Ardern-Jones Audrey T AT Dearnaley David P DP Horwich Alan A Khoo Vincent S VS Parker Christopher C CC Huddart Robert A RA Van As Nicholas N McCredie Margaret R MR English Dallas R DR Giles Graham G GG Hopper John L JL Easton Douglas F DF
Genetic epidemiology 20110718 6
Genome wide association studies have identified several single nucleotide polymorphisms (SNPs) that are independently associated with small increments in risk of prostate cancer, opening up the possibility for using such variants in risk prediction. Using segregation analysis of population-based samples of 4,390 families of prostate cancer patients from the UK and Australia, and assuming all familial aggregation has genetic causes, we previously found that the best model for the genetic suscepti ...[more]