Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population.
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ABSTRACT:
SUBMITTER: Reddy MV
PROVIDER: S-EPMC3952552 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
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Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population.
Reddy M V Prasad Linga MV Wang H H Liu S S Bode B B Reed J C JC Steed R D RD Anderson S W SW Steed L L Hopkins D D She J-X JX
Genes and immunity 20110127 3
The present study was conducted to assess genetic associations for type 1 diabetes (T1D) reported in previous genome-wide association studies (GWAS). A total of 21 previously reported single-nucleotide polymorphisms (SNPs) were genotyped by TaqMan assays in 1434 Caucasian T1D patients and 1864 normal controls from Georgia. Analysis of the samples identified 18 SNPs (PTPN22, INS, IFIH1, SH2B3, ERBB3, CTLA4, C14orf181, CTSH, CLEC16A, CD69, ITPR3, C6orf173, SKAP2, PRKCQ, RNLS, IL27, SIRPG and CTRB2 ...[more]
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