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Epidemiological and etiological characteristics of fever, thrombocytopenia and leukopenia syndrome in Henan Province, China, 2011-2012.


ABSTRACT: The Fever, Thrombocytopenia and Leukopenia Syndrome (FTLS) is caused by a bunyavirus known as the FTLS virus (FTLSV), which was recently discovered in China. We examined the epidemiological and etiological features of 637 laboratory-confirmed cases of FTLS with onset from January 2011 to December 2012 in Henan Province, China. The highest incidence of FTLS occurred between May and August: 76.5% of all laboratory-confirmed cases occurred during those four months. Of the laboratory-confirmed cases, 60.9% were in the 46-69 years old age groups; 96.1% (612/637) occurred in farmers; 98.1% (625/637) were reported from Xinyang Prefecture. During the same time period, 2047 cases were reported in China. The nucleotide and amino acid sequences of FTLSV strains identified during 2011-2012 in Henan Province were ? 96% identical. This findings provides insight for developing public-health interventions for the control and prevention of FTLS in epidemic area.

SUBMITTER: Huang X 

PROVIDER: S-EPMC3954591 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Epidemiological and etiological characteristics of fever, thrombocytopenia and leukopenia syndrome in Henan Province, China, 2011-2012.

Huang Xueyong X   Du Yanhua Y   Hu Xiaoning X   Ma Hongxia H   Wang Haifeng H   You Aiguo A   Kang Kai K   Chen Haomin H   Zhang Li L   Liu Guohua G   Xu Bianli B  

PloS one 20140314 3


The Fever, Thrombocytopenia and Leukopenia Syndrome (FTLS) is caused by a bunyavirus known as the FTLS virus (FTLSV), which was recently discovered in China. We examined the epidemiological and etiological features of 637 laboratory-confirmed cases of FTLS with onset from January 2011 to December 2012 in Henan Province, China. The highest incidence of FTLS occurred between May and August: 76.5% of all laboratory-confirmed cases occurred during those four months. Of the laboratory-confirmed cases  ...[more]

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