Unknown

Dataset Information

0

Efficient asymmetric synthesis of tryptophan analogues having useful photophysical properties.

ABSTRACT: Two new fluorescent probes of protein structure and dynamics have been prepared by concise asymmetric syntheses using the Schöllkopf chiral auxiliary. The site-specific incorporation of one probe into dihydrofolate reductase is reported. The utility of these tryptophan derivatives lies in their absorption and emission maxima which differ from those of tryptophan, as well as in their large Stokes shifts and high molar absorptivities.

SUBMITTER: Talukder P 

PROVIDER: S-EPMC3955165 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Efficient asymmetric synthesis of tryptophan analogues having useful photophysical properties.

Talukder Poulami P   Chen Shengxi S   Arce Pablo M PM   Hecht Sidney M SM  

Organic letters 20140106 2

Two new fluorescent probes of protein structure and dynamics have been prepared by concise asymmetric syntheses using the Schöllkopf chiral auxiliary. The site-specific incorporation of one probe into dihydrofolate reductase is reported. The utility of these tryptophan derivatives lies in their absorption and emission maxima which differ from those of tryptophan, as well as in their large Stokes shifts and high molar absorptivities. ...[more]

Similar Datasets

Unknown Synthesis of constrained analogues of tryptophan.
| S-EPMC4661003 | biostudies-literature
Unknown Synthesis of ?-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase.
| S-EPMC4948191 | biostudies-literature
Unknown Synthesis, characterization, and photophysical properties of three platinum(II) complexes bearing fluorescent analogues of the Di-2-pyridylmethane ligand.
| S-EPMC2879454 | biostudies-literature
Unknown Facile and efficient Lewis acid catalyzed synthesis of an asymmetric tetrazine useful for bio-orthogonal click chemistry applications.
| S-EPMC3834559 | biostudies-literature
Unknown Synthesis, photophysical and electrochemical properties of a mixed bipyridyl-phenanthrolyl ligand Ru(II) heteroleptic complex having trans-2-methyl-2-butenoic acid functionalities.
| S-EPMC6264457 | biostudies-literature
Unknown Iron-Catalyzed Synthesis, Structure, and Photophysical Properties of Tetraarylnaphthidines.
| S-EPMC7181034 | biostudies-literature
Unknown Carbazole- and Triphenylamine-Substituted Pyrimidines: Synthesis and Photophysical Properties.
| S-EPMC6540165 | biostudies-literature
Unknown The Synthesis and Photophysical Properties of Weakly Coupled Diketopyrrolopyrroles.
| S-EPMC8398321 | biostudies-literature
Unknown Efficient asymmetric synthesis of (+)-SCH 351448.
| S-EPMC1393291 | biostudies-literature
Unknown Azadioxatriangulenium: Synthesis and Photophysical Properties of Reactive Dyes for Bioconjugation.
| S-EPMC4817092 | biostudies-literature