Unknown

Dataset Information

0

The association of serum ionized calcium and vitamin D with adult cognitive performance.


ABSTRACT: High serum calcium levels have been associated with cognitive decline in older adults. These associations have not been studied in younger adults. The possible association of vitamin D with cognitive function, independent of calcium, is unknown.A cross-sectional study of associations of serum ionized calcium and 25-hydroxyvitamin D levels with cognitive function in younger adults (20-59 years) and older adults (60-90 years) was conducted using data from the US third National Health and Nutrition Examination Survey (NHANES III).Neither serum ionized calcium nor 25-hydroxyvitamin D was associated with cognitive function in either age group. For example, the confounder-adjusted mean difference in reaction time in young adults was 0.00 (95% confidence interval = -0.07 to 0.06) per 1 SD calcium.Our results do not support an important role for calcium or vitamin D in cognitive performance in adults.

SUBMITTER: Tolppanen AM 

PROVIDER: S-EPMC3957006 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

The association of serum ionized calcium and vitamin D with adult cognitive performance.

Tolppanen Anna-Maija AM   Williams Dylan M DM   Lawlor Debbie A DA  

Epidemiology (Cambridge, Mass.) 20110101 1


<h4>Background</h4>High serum calcium levels have been associated with cognitive decline in older adults. These associations have not been studied in younger adults. The possible association of vitamin D with cognitive function, independent of calcium, is unknown.<h4>Methods</h4>A cross-sectional study of associations of serum ionized calcium and 25-hydroxyvitamin D levels with cognitive function in younger adults (20-59 years) and older adults (60-90 years) was conducted using data from the US  ...[more]

Similar Datasets

| S-EPMC9299357 | biostudies-literature
| S-EPMC8314521 | biostudies-literature
| S-EPMC4348692 | biostudies-literature
| S-EPMC10789293 | biostudies-literature
| S-EPMC8049792 | biostudies-literature
| S-EPMC8478867 | biostudies-literature
| S-EPMC6766530 | biostudies-literature
| S-EPMC6025639 | biostudies-literature
| S-EPMC5549548 | biostudies-other
| S-EPMC6684569 | biostudies-literature