The association of serum ionized calcium and vitamin D with adult cognitive performance.

ABSTRACT:

Background

High serum calcium levels have been associated with cognitive decline in older adults. These associations have not been studied in younger adults. The possible association of vitamin D with cognitive function, independent of calcium, is unknown.

Methods

A cross-sectional study of associations of serum ionized calcium and 25-hydroxyvitamin D levels with cognitive function in younger adults (20-59 years) and older adults (60-90 years) was conducted using data from the US third National Health and Nutrition Examination Survey (NHANES III).

Results

Neither serum ionized calcium nor 25-hydroxyvitamin D was associated with cognitive function in either age group. For example, the confounder-adjusted mean difference in reaction time in young adults was 0.00 (95% co

SUBMITTER: Tolppanen AM 

PROVIDER: S-EPMC3957006 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature