Ontology highlight
ABSTRACT:
SUBMITTER: Brenmoehl J
PROVIDER: S-EPMC3957089 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Brenmoehl Julia J Albrecht Elke E Komolka Katrin K Schering Lisa L Langhammer Martina M Hoeflich Andreas A Maak Steffen S
International journal of biological sciences 20140311 3
Recent findings regarding the response of fibronectin type III domain-containing protein 5 (Fndc5) and irisin to exercise are partly controversial. While the 25 kDa form of Fndc5 can be observed in muscle and serum of different species, the ~12 kDa irisin band was not detectable up to now. The present study aimed to clarify whether irisin exists in its theoretical size of ~12 kDa in mice and if it is affected by exercise. Male mice were randomly assigned to a sedentary control group (CO), a grou ...[more]