Ontology highlight
ABSTRACT:
SUBMITTER: van der Plas MJ
PROVIDER: S-EPMC3960166 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
van der Plas Mariena J A MJ Andersen Anders S AS Nazir Sheresma S van Tilburg Nico H NH Oestergaard Peter R PR Krogfelt Karen A KA van Dissel Jaap T JT Hensbergen Paul J PJ Bertina Rogier M RM Nibbering Peter H PH
PloS one 20140319 3
Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. As haemostatic processes play an important role in wound healing, this study focused on the effects of maggot secretions on coagulation and fibrinolysis. The results showed that maggot secretions enhance plasminogen activator-induced formation of plasmin and fibrinolysis in a dose- and time-dependent manner. By contrast, coagulation was not affected by secretions. Biochemical studies indicated that a novel seri ...[more]