Ontology highlight
ABSTRACT:
SUBMITTER: Swerdlow NR
PROVIDER: S-EPMC3960985 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Swerdlow Neal R NR Light Gregory A GA Sprock Joyce J Calkins Monica E ME Green Michael F MF Greenwood Tiffany A TA Gur Raquel E RE Gur Ruben C RC Lazzeroni Laura C LC Nuechterlein Keith H KH Radant Allen D AD Ray Amrita A Seidman Larry J LJ Siever Larry J LJ Silverman Jeremy M JM Stone William S WS Sugar Catherine A CA Tsuang Debby W DW Tsuang Ming T MT Turetsky Bruce I BI Braff David L DL
Schizophrenia research 20140107 2-3
<h4>Background</h4>Startle inhibition by weak prepulses (PPI) is studied to understand the biology of information processing in schizophrenia patients and healthy comparison subjects (HCS). The Consortium on the Genetics of Schizophrenia (COGS) identified associations between PPI and single nucleotide polymorphisms in schizophrenia probands and unaffected relatives, and linkage analyses extended evidence for the genetics of PPI deficits in schizophrenia in the COGS-1 family study. These findings ...[more]