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Identification of an Emergent Porcine Circovirus-2 in Vaccinated Pigs from a Brazilian Farm during a Postweaning Multisystemic Wasting Syndrome Outbreak.

ABSTRACT: Three porcine circovirus-2 strains were isolated from pigs on a Brazilian farm during an outbreak, indicating a vaccine failure. They present identical genomic sequences, with high identities to other isolates that were also related to vaccination failures, supporting the recent theory about an antigen drift being associated with vaccine failures throughout the world.

SUBMITTER: Salgado RL

PROVIDER: S-EPMC3961721 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature

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Identification of an Emergent Porcine Circovirus-2 in Vaccinated Pigs from a Brazilian Farm during a Postweaning Multisystemic Wasting Syndrome Outbreak.

Salgado Rafael L RL Vidigal Pedro M P PM de Souza Luiz F L LF Onofre Thiago S TS Gonzaga Natália F NF Eller Monique R MR Bressan Gustavo C GC Fietto Juliana L R JL Almeida Márcia R MR Silva Júnior Abelardo A

Genome announcements 20140320 2

Three porcine circovirus-2 strains were isolated from pigs on a Brazilian farm during an outbreak, indicating a vaccine failure. They present identical genomic sequences, with high identities to other isolates that were also related to vaccination failures, supporting the recent theory about an antigen drift being associated with vaccine failures throughout the world. ...[more]

PMID: 24652974

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